In 2002, Christy Anderson, Wright-Way Rescue’s founder and Executive Director, visits a local animal control center and starts housing animals in her college dorm room at SIU Carbondale. Anderson then founds Wright-Way Rescue in 2003.

In 2006, Wright-Way opens its Admissions & Medical Services Campus to provide a state-of-the-art shelter for animals awaiting their forever homes. The Admissions and Medical Services Campus and Critical Care Center is located in Murphysboro, Illinois.  

In 2008, Wright-Way Rescue opens its doors to the Adoption Center in Niles, Illinois. By 2010, Wright-Way Rescue placed thousands of animals into loving homes in the Chicagoland area.

On October 2nd, 2013, a school bus crashed through the front of Wright-Way Rescue in Niles, Illinois. After 10 years of placing over 15,000 pets in homes, Wright-Way Rescue found itself homeless.

 In 2014, after nearly a year of being displaced due to the bus crash, Wright-Way Rescue opened its North Shore Humane Center in Morton Grove, Illinois.